Contribution of Regulatory and Structural Variations in the APOE Gene to Predicting Dyslipidemia
نویسندگان
چکیده
National Public Health Institute, Helsinki, Finland; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; Human Genetics Center and Institute of Molecular Medicine, The University of Texas Health Science Center, Houston, TX, USA
منابع مشابه
Contribution of regulatory and structural variations in APOE to predicting dyslipidemia.
The objective of this study was to evaluate 1) whether non single nucleotide polymorphisms-coding (non-cSNP) in the apolipoprotein E gene (APOE) identified by resequencing studies contribute to statistically explaining dyslipidemia if variations in the two cSNPs in exon 4 that define the 2, 3, and 4 alleles are ignored, and 2) whether the contribution of these additional SNPs persists when vari...
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